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Qin Lunxiu, Sun Haoting, Wang Chaoqun.. Application of the exosome in diagnosis and treatment of digestive system cancers[J]. Chinese Journal of Digestive Surgery, 2018, 17(4): 333-337. DOI: 10.3760/cma.j.issn.1673-9752.2018.04.003
Citation: Qin Lunxiu, Sun Haoting, Wang Chaoqun.. Application of the exosome in diagnosis and treatment of digestive system cancers[J]. Chinese Journal of Digestive Surgery, 2018, 17(4): 333-337. DOI: 10.3760/cma.j.issn.1673-9752.2018.04.003
shu

Application of the exosome in diagnosis and treatment of digestive system cancers

  • Department of General Surgery, Huashan Hospital, Cancer Metastasis Institute, Fudan University, Shanghai 200040, China

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  • The concept of precision medicine and precision oncology has been widely accepted. However, the application of this concept still faces many challenges. Exosome investigation is a hot spot in the field of liquid biopsy. Exosomes are extracellular vesicles composed of a lipid bilayer and contain proteins and nucleic acids which regulate cell-cell communication. Exosomes can be isolated and enriched in various body fluids. It has the advantages of micro-invasive, stable and biological active, and it fits well with the practice of precision medicine. In this review, authors discussed potential application and challenge of exosomes in early diagnosis and metastasis monitoring of gastric cancer.

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