Research progress of microvascular invasion in hepatocellular carcinoma

Hepatocellular carcinoma is one of the most common malignancies in the worldwide. Selected patients with hepatocellular carcinoma are candidates for curative resection, but nevertheless there is a high risk of tumor recurrence. Microvascular invasion (MVI) is an aggressive biological behavior and has repeatedly been identified as a risk factor for prognosis after curative treatment, meanwhile, it is now becoming increasingly concerned . It would be of great significance to distinguish MVI in an early stage and choose an appropriate treatment timely to get a definite improvement for the longterm survival in patients with hepatocellular carcinoma after curative treatment. This review focuses on some certain issues of MVI.