Progress of the diagnosis and treatment for adenocarcinoma of esophagogastric junction

The incidence of adenocarcinoma of esophagogastric junction is increasing worldwide during the past decades.Issues such as TNM classification, surgical approach, extent of lymphadenectomy, digestive tract reconstruction and perioperative adjuvant treatment remain unsolved. The debates on surgical approach and splenectomy have reached a consensus  according to the results of clinical trials, but most of the controversy are waiting for the final outcomes of randomized trials.