Signification of palliative operation in the treatment of colorectal cancer

The principle of R₀ resection for colorectal cancer (CRC) has been widely accepted based on the preoperative imaging evaluation. The surgeons should scientifically and strictly assess resectability of tumors and furthest reduce tumor residuals. Patients with initial unresectable CRC will give priority to conversion therapy and then undergo R₀ resection if converting into resectable tumors. Palliative operation for the patients who cannot receive R₀ resection according to the clinical assessment should strictly follow surgical indications and achieve wellplanned and clear surgical purposes. There is no evidence that the palliative operation or cytoreductive surgery benefits to survival of patients, and decreasing complications and improving quality of life through minimum wound are the basic principles.