Comments on 〖WTHX〗Associating liver partition and portal vein ligation for staged hepatectomy
-
Graphical Abstract
-
Abstract
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a recently developed 2 stage operation designed for patients with an advanced T stage hepatobiliary malignancy in the liver who cannot tolerate extensive liver resection because of the low future liver remnant volume. The dramatic liver regenerative response after the first staged operation results in dramatic and rapid hypertrophy in the future liver remnant. As a consequence, the second staged operation aiming to remove all tumors (R0 resection) can be carried out, usually, in about a week's time. This article traces the history of development of ALPPS, analyses its short term results, describes how the classical ALPPS is carried out, and lists out its modifications, techniques and variations.There are obvious advantages and disadvantages of ALPPS, which has its indications and contraindications.Initial results show ALPPS to have relatively high operative mortality and morbidity rates, although 0 mortality has been reported. The long term oncological result of ALPPS is unknown. There is also lack of data on ALPPS carried out on cirrhotic patients.
-
-
DownLoad: