Hepatic eosinophilic granuloma is a rare benign liver lesion, which results from granuloma formation due to chronic inflammation. Two patients were admitted to the Yantaishan Hospital and Yuhuangding Hospital from July 2008 to April 2012, respectively. The results of laboratory examination showed the elevation of peripheral blood eosinophils, and ultrasound examinations revealed lowecho masses in the liver and no blood flow was detected. The results of computed tomography showed hypoattenuation lesions with welldemarcated boundary. After intravenous administration of contrast angent, the lesions demostrated delayed heterogeneous enhancement with internal grid. The results of magnetic resonance imaging of 1 patient showed the lesion had slight hyperintensity to the surrounding liver parenchyma on T1weighted images, and slight high signal with low signal separation strip inside on fatsuppressed T2weighted images. An obvious high signal was detected in diffusion weighted imaging. Familiarity with the imaging characteristics and combination of the elevation of peripheral eosinophil can help surgeons to make a suggestive diagnosis.
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