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Pang Feixiong, Huang Xiaochun, Liu Hongjun, et al. Application value of laparoscopic‑assisted total liver transplantation[J]. Chinese Journal of Digestive Surgery, 2024, 23(11): 1445-1451. DOI: 10.3760/cma.j.cn115610-20240913-00418
Citation: Pang Feixiong, Huang Xiaochun, Liu Hongjun, et al. Application value of laparoscopic‑assisted total liver transplantation[J]. Chinese Journal of Digestive Surgery, 2024, 23(11): 1445-1451. DOI: 10.3760/cma.j.cn115610-20240913-00418

Application value of laparoscopic‑assisted total liver transplantation

Funds: 

Science and Technology Plan Project of Guangxi Zhuang Autonomous Region AD22035101

Key Laboratory of Health Commission of Guangxi Zhuang Auto⁃nomous Region ZZH2020006

More Information
  • Corresponding author:

    Lai Yanhua, Email: 1379771812@qq.com

  • Received Date: September 12, 2024
  • Objective 

    To investigate the application value of laparoscopic‑assisted total liver transplantation.

    Methods 

    The retrospective and descriptive study was conducted. The clinical data of 9 pairs of donors and recipients who underwent laparoscopic‑assisted total liver transplanta-tion in People′s Hospital of Guangxi Zhuang Autonomous Region from January to April 2024 were collected. Of the donors, there were 8 males and 1 female, aged (39±18)years and with body mass index (BMI) of (20±4)kg/m2. Of the recipients, there were 7 males and 2 females, aged (41±13)years and with BMI of (24±4)kg/m2. Measurement data with normal distribution were represented as Mean±SD. Count data were described as absolute numbers.

    Results 

    (1) Surgical conditions. Of the 9 recipients, 7 recipients underwent laparoscopic‑assisted total liver transplantation successfully, 1 recipient with severe portal hypertension converted to open surgery with reverse L‑shaped incision due to the hemorrhage during the dissection of the first hepatic portal after completing liver mobilization under laparoscopy, and 1 recipient underwent trans‑umbilical extension incision through the middle of the epigastric region due to the limited space for operation in the implantation of the donor liver. The total operation time for 7 recipients who successfully underwent laparoscopic-assisted total liver transplantation was (648±31)minutes, with a time of anhepatic phase of (57±5)minutes, the volume of intraoperative blood loss of (1 322±627)mL, the donor liver mass of (1 195±232)g, and the ratio of donor liver mass to recipient body mass of 1.86%±0.42%. The operation time for laparoscopic liver dissection and porta hepatis dissection in 8 recipients during surgery was (212±35)minutes. (2) Postoperative conditions. All 9 recipients recovered smoothly after surgery, without any vascular or biliary related complications, and the surgical incision recovered well. The duration of postoperative hospital stay of 7 recipients who successfully underwent laparoscopic-assisted total liver transplantation was (14.2±2.0)days. (3) Follow‑up. All 9 recipients were followed up for 3 months after surgery. During the follow‑up period, there was no vascular or bile duct related complication.

    Conclusion 

    Laparoscopic‑assisted total liver transplantation can be applied to recipients who meet surgical conditions and achieve good short‑term clinical efficacy.

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