Clinical efficacy of laparoscopic sleeve gastrectomy in obese adolescents

Shan Xiaodong; Zhu Saisai; Yan Yu; Chu Xuehui; Sun Xitai

doi:10.3760/cma.j.cn115610-20220927-00552

Chinese Journal of Digestive Surgery > 2022 > 21(12): 1567-1572. > DOI: 10.3760/cma.j.cn115610-20220927-00552

Shan Xiaodong, Zhu Saisai, Yan Yu, et al. Clinical efficacy of laparoscopic sleeve gastrectomy in obese adolescents[J]. Chinese Journal of Digestive Surgery, 2022, 21(12): 1567-1572. DOI: 10.3760/cma.j.cn115610-20220927-00552

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Clinical efficacy of laparoscopic sleeve gastrectomy in obese adolescents

1.
Department of General Surgery, Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing210008, China
2.
Nanjing University Medical School, Nanjing210008, China
3.
Southeast University Medical School, Nanjing210009, China

Funds:

Nanjing Medical Science and Technique Development Foundation YKK20078

New Technology Development Foundation of Nanjing Drum Tower Hospital XJSFZJJ201904

More Information

Corresponding author:
Sun Xitai, Email: sunxitai@vip.qq.com
Received Date: September 26, 2022
Available Online: July 04, 2024

Graphical Abstract

Abstract

Abstract

Objective
To investigate the clinical efficacy of laparoscopic sleeve gastrectomy in obese adolescents.
Methods
The retrospective and descriptive study was conducted. The clinical data of 37 obese adolescents who were admitted to Drum Tower Hospital Affiliated to Nanjing University Medical School between July 2016 and August 2020 were collected. There were 18 males and 19 females, aged 18(range, 13‒19)years. All patients underwent laparoscopic sleeve gastrec-tomy. Observation indicators: (1) surgical and postoperative situations; (2) follow-up. The patients were followed up by outpatient review to detect body weight, blood glucose, blood lipid, blood pressure, nutrition situation and related complications at 3, 6 and 12 months after operation. The follow-up was up to August 2021. Measurement data with normal distribution were represented as Mean±SD. Repeated measurement data were analyzed by Repeated Measures Anova. Measurement data with skewed distribution were represented by M(range). Count data were expressed as absolute numbers or percentages.
Results
(1) Surgical and postoperative situations. All 37 patients under-went laparoscopic sleeve gastrectomy successfully, the operative time was (50±7)minutes, the volume of intraoperative blood loss was (53±17)mL, and the duration of postoperative hospital stay was (3.0±0.5)days. Of the 37 patients, 2 cases had puncture infection. There was no complication such as bleeding occurred. (2) Follow-up. Of the 37 patients, 35, 31 and 22 cases were followed up at postoperative 3, 6 and 12 months, respectively. There was no anemia, malnutrition, trace element deficiency or other nutrition-related complications during the follow-up, and there was no death. The body mass, body mass index, homeostasis model assessment-insulin resistance, triglyceride, total cholesterol, systolic pressure, diastolic pressure, vitamin D, folate of the 37 patients were (117±19)kg, (40±5)kg/m², 6.59(range, 2.84‒28.02), (1.6±0.7)mmol/L, (4.5±0.7)mmol/L, (141±22)mmHg (1 mmHg=0.133 kpa), (84±18)mmHg,(14±5)μg/L, (10±5)μg/L before the surgery, and (81±15)kg, (27±4)kg/m², 2.69(range, 1.08‒9.71), (0.9±0.5)mmol/L, (4.5±0.7)mmol/L, (115±15)mmHg, (70±11)mmHg, (23±10)μg/L, (9±5)μg/L at postoperative 12 months. There were significant differences in the time effect of above indicators (F_time=214.14, 160.37, 12.66, 11.77, 2.90, 18.08, 11.32, 8.61, 5.04, P<0.05). The percentages of excess of body mass index lost of the 37 patients were 48%±19%, 77%±28% and 89%±24% at postoperative 3, 6 and 12 months, the percentages of excess weight loss were 42%±13%, 63%±17% and 75%±18%, the percentages of total body weight loss were 18%±5%, 26%±6% and 34%±7%, respectively. There were significant differences in the time effect of above indicators (F_time=83.96, 107.24, 109.06, P<0.05). The hemoglobin A1c was 4.8%, 5.0%, 5.1% and 4.9%, 5.2%, 5.2% in the 2 patients with type 2 diabetes at postoperative 3, 6 and 12 months, respectively, and they were relieved without drug treatment.
Conclusion
Laparoscopic sleeve gastrectomy has definite short-term clinical efficacy in the treatment of adolescent obesity, which can effectively reduce excess body weight and improve the metabolic complications of insulin resis-tance, dyslipidemia and hypertension.
- Obesity,
- Adolescent,
- Metabolic diseases,
- Laparoscopic sleeve gastrectomy,
- Efficacy

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References (39)

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