Abstract: The detection rate of early gastric cancer in China shows an increasing trend year by year, and endoscopic treatment based on evidence‑based medicine has become one of the major modalities for early gastric cancer. Endoscopic diagnosis, imaging diagnosis and pathological evaluation are applied to evaluate early gastric cancer which is suitable for endoscopic resection. However, endoscopic resection has surgical risks and relevant complications, including gastric per-foration, hemorrhage, and tumor residuals. Therefore, it is necessary to strictly follow the surgical indications of endoscopic resection for early gastric cancer, master the endoscopic resection technique, choose a reasonable strategy of endoscopic resection, and draw up a protocol of salvage surgery for tumor residue after endoscopic resection, which will improve the curability and surgical safety for early gastric cancer. The authors consult relevant research and systematically elaborate on the strategy of endoscopic resection for early gastric cancer and salvage surgery.