Abstract: Type 2 diabetes mellitus (T2DM) usually becomes complicated and unmanageable when combing with metabolic syndromes of obesity, hypertension and hyperlipidemia. Medical treatment generally adopts non surgical management, such as diet control, exercise and oral medications; surgical treatment can improve the condition of patients with T2DM and the metabolic syndromes. In this article, the multi disciplinary treatment of a patient with T2DM and obesity in the Third Xiang ya Hospital of Central South University was analyzed, so as to provide a new way for the treatment of this disease.