Abstract: he feasibility and safety of laparoscopic colorectal cancer resection have been gradually accepted as the fast development of minimally invasive surgery. However, there are few reports about the detailed skills and key points in the surgical techniques because of low incidence of transverse colon cancer and involvement of pancreas, stomach, spleen and kidney. From July 2007 to June 2009, 29 patients with transverse colon cancer who were admitted to the People′s Hospital of Guangdong Province received laparoscopic transverse colon cancer resection. The skills and key points were summarized in order to decrease the incidence of complications and shorten the laparoscopic learning curve.