Abstract: With diversification of treatment methods and standardization of multidisciplinary diagnosis and treatment, several strategies including down-staging of advanced hepatocellular carcinoma(HCC) by hepatic artery catheterization, radiotherapy, targeted therapy and other comprehensive treatments, rapid increasement of the future liver remnant through portal vein embolization or combined with hepatic septation and portal vein ligation, routine anti-viral therapy and liver protecting treatment have led to success conversion from advanced HCC or HCC with insufficiency of liver remnant function to resectable cancer, which has become an important way to improve the prognosis of HCC and attracted a lot of attention in clinical research. In this article, the author has further elaborated on the connotation, strategy and progression of the conversion therapy for HCC.