Abstract: Laparoscopic anatomical resection (LAR) is a highly-demanding and high risky procedure. Traditional single-surgeon technique appears to be frustrating when dealing with intro-operative emergency and ensuring the safety of complicated LAR. The authors′ department has applied two-surgeon technique when performing LAR since 2014. In complicated cases of LAR, two skillful surgeons cooperate to perform surgeries. The two surgeons stand at each side of the patient and switch their duties as the surgeon or the assistant during the operation. Experience of the authors’ department shows that compared with single-surgeon technique, two-surgeon technique can help better deal with intro-operative accidental events such as hemorrhage and guarantee the safety of LAR, as well as enhance the efficiency and quality of procedures. Two-surgeon technique benefits team building and training young laparoscopic liver surgeons, and help them pass the learning curve more safely and quickly.