背驮式肝移植及其改良技术的临床应用

Clinical application of piggyback liver transplantation and modified surgery

  • 摘要: Starzl于1963年率先施行原位肝移植,随后肝移植技术持续发展。Tzakis于1989年报道背驮式肝移植(PBLT)。两种手术方式的根本区别是:原位肝移植在切除病变肝脏后,将供肝管道与受者同名管道行端端吻合;PBLT保留受者的肝静脉,并将供肝肝上下腔静脉与受者成型的肝静脉行端-端吻合。在肝移植应用过程中,上述两种手术方式均出现不能完全适应临床需要的情况。自1993年以来,笔者施行了系列基于PBLT的改良式背驮式肝移植(APBLT),现对APBLT的技术特点及其临床应用进行系统探讨。

     

    Abstract: Orthotopic liver transplantation (OLT) was first implemented by Starzl in 1963. With the development of liver transplantation, Tzaris was the first to report piggyback liver transplantation (PBLT) in 1989. The fundamental difference between OLT and PBLT: end to end vascular anastomosis between the donor and recipient is performed after diseased liver resection with the posthepatic inferior vena cava in OLT, while PBLT is to preserve the recipient′s hepatic vein and end to end vascular anastomosis between interior vena cava of donor and shaped hepatic vein is performed. However in the clinical practice, the above two techniques cannot meet the needs of clinical liver transplantation technology. Since 1993 the author has implemented a series of improvements in liver transplantation technology based on PBLT and performed ameliorated piggyback liver transplantation (APBLT). This article focuses on the technical characteristics and clinical application of APBLT.

     

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