Abstract:  Minimally invasive surgery has got a great development in the past 30 years. Currently, a series of new technique and novel technology have been introduced, which bring us a new prospect and also new challenges. In surgery methods, Adenocarcinoma of esophagogastric junction (AEG) is also a hot topic recently, especially the gastrointestinal tract reconstruction of AEG in total laparoscopic surgery. Transanal total mesorectal excision has several advantages in difficult cases of lower rectal cancer, but is still under debate for oncological safety. 3D laparoscopic surgery, glass-free 3D laparoscopic surgery, 4K laparoscopic surgery and laparoscopic indocyanine green fluorescence imaging are innovative technology in minimally invasive surgery at home and abroad. The fusion and hybrid of the new technique and novel technology might be the future of the minimally invasive surgery.