Abstract: Liver transplantation makes it possible to cure portal hypertension thoroughly. A new pattern of combined application of multiple treatments based on liver transplantation has emerged. Conventional surgical treatments such as splenectomy, devascularization and transjugular intrahepatic portosystemic shunting have important effects on the prognosis of liver transplant recipients. Portal vein stenosis, thrombosis as well as small-for-size liver graft lead to post-transplant portal hypertension and liver dysfunction. The author in this article provides an overview of the effects of various conventional treatments on the prognosis of recipients and the treatment of portal hypertension after liver transplantation, aiming to seek for optimal strategy.