食管空肠π形Roux-en-Y吻合术在全腹腔镜全胃切除术中的应用价值

Application value of π-shaped Roux-en-Y esophagojejunostomy in totally laparoscopic total gastrectomy

  • 摘要: 目的:探讨食管空肠π形Roux-en-Y吻合术在全腹腔镜全胃切除术中的应用价值。
    方法:采用回顾性描述性研究方法。收集2016年10月至2017年3月首都医科大学附属北京友谊医院收治的 3例行全腹腔镜全胃切除术患者的临床病理资料。采用π形Roux-en-Y吻合术行食管空肠吻合。术后病理学分期为Ⅱ期以上患者行术后辅助化疗,方案为奥沙利铂+替吉奥。观察指标:(1)手术及术后恢复情况。(2)随访和生存情况。采用门诊和电话方式进行随访,了解患者术后辅助治疗和生存情况。随访时间截至2018年3月。
    结果:(1)手术及术后恢复情况: 3例患者均顺利完成全腹腔镜全胃切除术,食管空肠吻合采用π形Roux-en-Y吻合术。其中病例1清扫第11p组淋巴结时损伤脾血管,顺利止血;病例2、3术中未发生并发症。病例1、2、3手术时间分别为376、290、284 min,消化道重建时间分别为26、30、24 min,术中出血量分别为500、100、200 mL,术后肛门首次排气时间分别为2、3、3 d,术后引流管拔除时间分别为4、4、5 d。病例3术后发生左侧胸腔积液,经穿刺引流后痊愈;病例1和2术后未发生并发症。3例患者术后均未发生吻合口相关并发症。术后病理学检查情况:病例1、2、3淋巴结清扫数目分别为20、17、20枚,肿瘤TNM分期分别为T1aN0M0、T3N3M0、T1bN0M0期。病例1、2、3术后住院时间分别7、8、11 d。(2)随访和生存情况:3例患者均获得术后随访,病例1、2、3随访时间分别为18、16、12个月。随访期间,病例2行术后辅助化疗,于术后12个月复查时发现多发肝转移灶,行紫杉醇+希罗达姑息化疗;病例1和3无瘤生存。
    结论:采用π形Roux-en-Y吻合术行全腹腔镜全胃切除食管空肠吻合安全可行,可作为消化道重建的一种选择。

     

    Abstract: Objective:To investigate the application value of πshaped esophagojejunostomy in totally laparoscopic total gastrectomy.
    Methods:The retrospective and descriptive study was conducted. The clinicopathological data of 3 patients who underwent totally laparoscopic total gastrectomy in the Beijing Friendship Hospital of Capital Medical University between October 2016 and March 2017 were collected. Patients received πshaped Roux-en-Y esophagojejunostomy. Patients who were diagnosed with Ⅱ and above stages by pathological examination underwent postoperative adjuvant chemotherapy with oxaliplatin + tegafur gimeracil oteracil. Observation indicators: (1) surgical and postoperative recovery situations; (2) followup and survival situations. The followup using outpatient examination and telephone interview was performed to detect postoperative adjuvant therapy and survival up to March 2018.
    Results:(1) Surgical and postoperative recovery situations: 3 patients underwent successfully totally laparoscopic total gastrectomy, and πshaped Roux-en-Y esophagojejunostomy was also performed. Case 1 had injury of spleen vessel when No 11p lymph nodes were dissected and then received successful hemostasis, and case 2 and 3 didn′t have complication. Operation time, digestive tract reconstruction time, volume of intraoperative blood loss, time to anal exsufflation and postoperative drainagetube removal time of case 1, 2 and 3 were respectively 376 minutes, 290 minutes, 284 minutes and 26 minutes, 30 minutes, 24 minutes and 500 mL, 100 mL, 200 mL and 2 days, 3 days, 3 days and 4 days, 4 days, 5 days. Case 3 with left pleural effusion was cured by puncture and drainage treating, and case 1 and 2 didn′t have complication. Three patients were not complicated with anastomotic stomarelated complicaions. Results of postoperative pathological examination: number of lymph node dissected and TNM staging of case 1, 2 and 3 were respectively 20, 17, 20 and T1aN0M0 staging, T3N3M0 staging, T1bN0M0 staging. Duration of hospital stay in case 1, 2 and 3 was respectively 7 days, 8 days and 11 days. (2) Followup and survival situations: 3 patients were followed up, and followup time of case 1, 2 and 3 was respectively 18 months, 16 months, 12 months. During the followup, case 2 received postoperative adjuvant therapy, and then underwent palliative treatment of Paclitaxel and Xeloda after the case was rechecked out multiple liver metastases at postoperative month 12. Case 1 and 3 had diseasefree survival.
    Conclusion:The πShaped esophagojejunostomy is safe and feasible for totally laparoscopic total gastrectomy, and it can be used as an alternative to digestive tract reconstruction.

     

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