肝左外叶粘贴式悬吊在单孔腹腔镜左季肋区手术中的应用价值

Application value of the adhesive suspension of left lateral lobe of liver in transumbilical single-port laparoscopic left upper abdominal surgery

  • 摘要: 目的:探讨肝左外叶粘贴式悬吊在单孔腹腔镜左季肋区手术中的应用价值。
    方法:采用回顾性横断面研究方法。收集2010年1月至2016年10月中国医科大学附属盛京医院收治的112例行单孔腹腔镜手术患者的临床资料。患者行单孔腹腔镜左季肋区手术,术中采用肝左外叶粘贴式悬吊暴露手术视野。观察指标:(1)术中情况:患者完成手术情况、手术方式、肝脏粘贴悬吊时间、总手术时间、术中肝脏粘贴悬吊的相关并发症。(2)术后情况:谷丙转氨酶(ALT)和谷草转氨酶(AST)术前和术后情况、住院费用、住院时间。(3)随访情况:获得随访的人数、随访时间、随访期间并发症发生情况。采用门诊和电话进行随访,了解患者术后并发症的发生情况。随访时间截至2017年6月。正态分布的计量资料以±s表示,重复测量资料采用重复测量方差分析。
    结果:(1)术中情况:112例患者均成功完成单孔腹腔镜左季肋区手术,无中转为多孔法或开腹手术。112例患者中,胃癌根治术30例,胃部分切除术23例,食管Heller肌切开+Dor胃底折叠术13例,胃大部切除术11例,胰体尾切除术11例,食管裂孔疝修补+胃底折叠术10例,全胃切除术3例,脾切除术3例,脾切除+贲门周围血管离断术3例,胰尾部切除术3例,单纯胃底折叠术1例,脾动脉瘤切除术1例。112例患者肝脏粘贴悬吊时间为(1.4±0.4)min,总手术时间为(192.0±91.3)min。112例患者术中均未发生肝脏裂伤、肝脏包膜下血肿等悬吊相关并发症。(2)术后情况:112例患者中,6例术前ALT、AST轻度升高,其中2例术后恢复正常,1例术后第1天升高、第3天恢复正常,3例术后1周仍轻度升高;106例患者术前ALT、AST均正常,其中31例术后第1天升高(28例术后1周内恢复正常、3例轻度升高),75例术后正常。112例患者术前ALT、AST分别为(16±11) U/L和(18±7)U/L,术后第1天为(31±21)U/L和(34±26)U/L,术后1周为(19±17)U/L和(19±12)U/L;术前与术后第1天比较,差异有统计学意义(F=36.353,29.792,P<0.05);术前与术后1周比较,差异无统计学意义(F=2.905,1.284,P>0.05)。112例患者住院费用为(45 231±20 440)元,手术相关费用为(23 511±9 609)元,住院时间为(6.0±1.9)d。(3)随访情况:112例患者术后均获得随访,随访时间为1.0~3.0个月,中位随访时间为1.6个月。患者随访期间均未发生明显并发症。
    结论:肝左外叶粘贴式悬吊方法操作简单,安全,暴露效果满意,适合应用于单孔腹腔镜左季肋区手术中辅助暴露手术视野。

     

    Abstract: Objective:To investigate the application value of the adhesive suspension of left lateral lobe of liver in transumbilical single-port laparoscopic left upper abdominal surgery.
    Methods:The retrospective cross-sectional study was conducted. The clinical data of 112 patients who underwent single-port laparoscopic left upper abdominal surgery in the Shengjing Hospital of China Medical University between January 2010 and October 2016 were collected. Patients underwent single-port laparoscopic left upper abdominal surgery, and intraoperative surgical fields were exposed through adhesive suspension of left lateral lobe of liver. Observation indicators: (1) intraoperative situations: surgical completion, surgical procedures, time of liver adhesive suspension, total operation time and intraoperative liver adhesive suspension-related complications; (2) postoperative situations: pre- and post-operative alanine transaminase (ALT) and aspartate transaminase (AST) levels, hospital expenses and duration of hospital stay; (3) follow-up: number of patients with follow-up, follow-up time, complications during follow-up. Follow-up using outpatient examination and telephone interview was performed to detect postoperative complications up to June 2017. Measurement data with normal distribution were represented as ±s. Repeated measurement data were analyzed using the repeated measures ANOVA.
    Results:(1) Intraoperative situations: 112 patients underwent successfully single-port laparoscopic left upper abdominal surgery, without conversion to multi-port surgery or open surgery. Of 112 patients, 30, 23, 13, 11, 11, 10, 3, 3, 3, 3, 1 and 1 underwent radical resection of gastric cancer, partial gastrectomy, esophageal Heller myotomy + Dor fundo-plication, subtotal gastrectomy, resection of body and tail of pancreas, paraoesophageal hiatal hernia repair + fundoplication, total gastrectomy, splenectomy, splenectomy + devascularization, pancreatic tail resection, simple fundoplication and splenic artery aneurysm resection, respectively. Time of liver adhesive suspension and total operation time in 112 patients were respectively (1.4±0.4)minutes and (192.0±91.3) minutes. There was no hepatic laceration, hepatic subcapsular hematoma and other complications. (2) Postoperative situations: of 112 patients, preoperative ALT and AST levels of 6 patients were mildly elevated, postoperative ALT and AST levels in 2 of 6 patients returned to normal, that in 1 of 6 patients were elevated at day 1 postoperatively and returned to normal at day 3 postoperatively, and that in 2 of 6 patients remained mildly elevated at week 1 postoperatively; preoperative ALT and AST levels of 106 patients were normal, ALT and AST levels in 31 of 106 patients were elevated at day 1 postoperatively (that in 28 patients returned to normal within week 1 postoperatively, and that in 3 patients remained mildly elevated), and that in 75 of 106 patients returned to normal. ALT and AST levels of 112 patients were (16±11)U/L, (18±7)U/L before operation and (31±21)U/L, (34±26)U/L at day 1 postoperatively and (19±17)U/L, (19±12)U/L at week 1 postoperatively, respectively, with statistically significant differences in ALT and AST levels before operation and at day 1 postoperatively (F=36.353, 29.792, P<0.05), and no statistically significant difference in ALT and AST levels before operation and at week 1 postoperatively (F=2.905, 1.284, P>0.05). Hospital expenses, surgery-related expenses and duration of hospital stay were (45 231±20 440)yuan, (23 511±9 609)yuan and (6.0±1.9)days, respectively. (3) Follow-up: 112 patients were followed up for 1.0-3.0 months, with a median time of 1.6 months. During the follow-up, there were no obvious complications.
    Conclusions:Adhesive suspension of left lateral lobe of liver is simple and safe, with satisfactory exposure effects, and it is suitable for the better operative field exposure in single-port laparoscopic left upper abdominal surgery.

     

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