胃癌的转化医学研究

Research progress of translational medicine for gastric cancer

  • 摘要: 胃癌是全世界常见消化道恶性肿瘤。近年来,手术方式的变革和放化疗方案的优化对患者生存时间和生命质量改善有限。随着基因测序技术、诊断与治疗靶点、分子分型等研究的发展和医学思维模式的转变,胃癌综合诊断与治疗研究逐渐面向精准和大数据发展。目前学术界亟需将胃癌多维组学数据与临床资料充分整合,形成有利于临床转化的研究模式,推动胃癌精准医疗进步。

     

    Abstract: Gastric cancer is one of the most common malignant digestive tumors globally. The comprehensive treatment based on surgery of gastric cancer can not satisfy the purpose to reduce morbidity and mortality. In recent years, translational medicine has emerged with the rapid development of basic medical research, such as molecular biology, and the change of medical patterns. The core of translational medicine is to establish a fast conversion channel between basic research and clinical applications which could translate basic research results into theories, technologies and products for clinical practice. In the present paper, the research progress of translational medicine in the diagnosis and treatment of gastric cancer will be summarized, and the role of translational medicine for precise treatment of gastric cancer will be discussed.

     

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