Abstract: Colorectal cancer is one of the most common malignant cancers in the world. In China, the incidence of colo rectal cancer is increasing year by year, with the characteristics of the insidious onset, long time canceration and high cure rate of early stage tumors. These will lead to the crucial significance of prevention and screening work for reducing the incidence of colorectal cancer, improving the cure rate and reducing the relevant medical costs. Screening and prevention of colorectal cancer has been carried out for nearly half a century in the world. However, systematic screening began at the beginning of this century in China. This article reviewed the results, methods, strategies and main problems of colorectal cancer screening in China and abroad.