完全达芬奇机器人手术系统胃癌根治术的临床疗效

Clinical efficacy of totally Da Vinci robotic surgical system in radical gastrectomy of gastric cancer

  • 摘要: 目的:探讨完全达芬奇机器人手术系统胃癌根治术的安全性和可行性。
    方法:采用回顾性横断面研究方法。收集2016年6月至2017年8月陆军军医大学西南医院收治的30例行完全达芬奇机器人手术系统胃癌根治术患者的临床资料。手术方法参照《胃癌胃切除手术加速康复外科专家共识(2016版)》。观察指标:(1)手术及术后恢复情况。(2)随访情况。采用门诊和电话方式进行随访,了解患者术后生存和肿瘤复发、转移情况。随访时间截至2017年9月。正态分布的计量资料以±s表示,偏态分布的计量资料以M(范围)表示。
    结果:(1)手术及术后恢复情况:30例患者均成功完成完全达芬奇机器人手术系统胃癌根治术,无中转腹腔镜或开腹患者。30例患者中,21例行远端胃大部切除术(其中1例行Billroth Ⅰ式吻合术、20例行Billroth Ⅱ式吻合术),9例行全胃切除术(均行RouxenY吻合术);1例行D1根治术, 24例行D2根治术,5例行D 2+根治术。30例患者术中淋巴结清扫数目为(34±12)枚,腹壁切口长度为 (4.1±0.5)cm,手术时间为(269±52)min,消化道重建时间为(49±9)min;其中21例远端胃大部切除术患者上述指标分别为(31±21)枚,(4.0±0.9)cm,(253±61)min,35 min(1例Billroth Ⅰ式吻合术)和(38±10)min(20例Billroth Ⅱ式吻合术),9例全胃切除术患者上述指标分别为(46±12)枚,(4.0±0.5)cm,(325± 30)min,(64±12)min。30例患者术中出血量为(78±43)mL,术后疼痛评分为(2.5±0.5)分,术后首次下床活动时间为(33±8)h,术后胃肠功能恢复时间为(59±13)h,术后首次进流质食物时间为(66±32)h,术后腹腔引流管拔除时间为(64±21)h。30例患者中,2例发生术后并发症,其中左下肺感染1例、腹腔脓肿1例,均经保守治疗后治愈。30例患者术后住院时间为(7±5)d。(2)随访情况:30例患者均获得术后随访,随访时间为1.0~15.0个月,中位随访时间为7.5个月。随访期间,2例患者分别于术后半年、1年死于肿瘤复发,1例患者术后1年肿瘤复发仍带瘤生存,其余27例患者无瘤生存。
    结论:完全达芬奇机器人手术系统胃癌根治术安全可行,近期疗效较好。

     

    Abstract: Objective:To investigate the safety and feasibility of totally Da Vinci robotic surgical system in the radical gastrectomy of gastric cancer.
    Methods:The retrospective crosssectional study was conducted. The clinical data of 30 patients who underwent radical gastrectomy of gastric cancer via totally Da Vinci robotic surgical system in the Southwest Hospital of Army Medical University between June 2016 and August 2017 were collected. Surgical methods were selected according to Expert consensus on enhanced recovery after gastrectomy for gastric cancer (2016 edition). Observation indicators: (1) surgical and postoperative situations; (2) followup. Followup using outpatient examination and telephone interview was performed to detect the patients′ postoperative survival and tumor recurrence and metastases up to September 2017. Measurement data with normal distribution were represented as ±s and measurement data with skewed distribution were represented as median (range).
    Results: (1) Surgical and postoperative situations: 30 patients underwent radical gastrectomy of gastric cancer using totally Da Vinci robotic surgical system, without conversion to laparoscopic or open surgery. Of 30 patients, 21 underwent distal subtotal gastrectomy including 1 with Billroth Ⅰ anastomosis and 20 with Billroth Ⅱ anastomosis, 9 underwent total gastrectomy with RouxenY anastomosis. Of 30 patients, 1 underwent D1 radical gastrectomy, 24 underwent D2 radical gastrectomy and 5 underwent D 2+ radical gastrectomy. The number of lymph node detected, length of abdominal incision, operation time and time of digestive tract reconstruction were 34±12, (4.1±0.5)cm,(269±52)minutes and (49±9)minutes in 30 patients, including 31±21, (4.0±0.9)cm, (253±61)minutes, 35 minutes (1 with Billroth Ⅰ anastomosis) and (38±10)minutes (20 with Billroth Ⅱ anastomosis) in 21 patients undergoing distal subtotal gastrectomy and 46±12, (4.0±0.5)cm, (325±30)minutes, (64±12)minutes in 9 patients undergoing total gastrectomy. The volume of intraoperative blood loss, postoperative pain score, time for outofbed activity, time of gastrointestinal function recovery, time for fluid food intake and time of drainage tube removal were (78±43)mL, 2.5±0.5, (33±8)hours, (59±13)hours, (66±32)hours and (64±21)hours, respectively. Of 30 patients, 2 with postoperative complications were cured by conservative treatment, including 1 of left lower lobe infection and 1 of abdominal abscess. Duration of postoperative hospital stay was (7± 5)days. (2) Followup: 30 patients were followed up for 1.0-15.0 months, with a median time of 7.5 momths. During followup, 2 patients died of tumor recurrence at postoperative half year and 1 year, 1 patient still survived with tumor recurrence and other 27 patients had tumorfree survival.
    Conclusion:The totally Da Vinci robotic surgical system is safe and feasible in the radical gastrectomy of gastric cancer, with good shortterm outcomes.

     

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