Abstract: Objective:To systematically evaluate the clinical efficacy of bariatric surgery for elderly (age ≥60 years) or nonelderly (age <60 years) obese patients.
Methods:Literatures were researched using PubMed, Embase, Cochrane Library from January 2006 to June 2016 with the key words including “bariatric surgery, metabolic surgery, gastric bypass, gastric band, sleeve gastrectomy, biliopancreatic diversion, elderly, aged, over 60 years”. The cohort study about clinical efficacy of bariatric surgery for elderly or nonelderly obese patients were received and enrolled, and surgical procedures were unrestricted. Patients with age ≥60 years and with age <60 years were respectively allocated into the elderly group and nonelderly group. Two reviewers independently screened literatures, extracted data and assessed the risk of bias. Count data were described as odds ratio (OR) and 95% confidence interval (CI). The heterogeneity of the studies was analyzed using the I2 test.
Results:Eleven retrospective studies were enrolled in the Meta analysis, and the total sample size was 9 913 patients, including 792 in the elderly group and 9121 in the nonelderly group. The results of Meta analysis showed that there were no statistically significant differences in the early mortality, incidence of postoperative early complication, remission rates of postoperative diabetes, postoperative hypertension, dyslipidemia and obstructive sleep apnea syndrome between elderly group and nonelderly group (OR=3.31, 1.94, 1.00, 0.61, 0.99, 1.40, 95%CI: 0.86-12.77, 1.01-3.74, 0.66-1.50, 0.34-1.10, 0.42-2.29, 0.72-2.72，P>0.05).
Conclusion:The safety and clinical efficacy of bariatric surgery in the elderly obese patients are equivalent to that of nonelderly patients.