Abstract: Due to the theoretical and technique limitation of traditional surgery, surgical treatment of complex intrahepatic biliary diseases was left for an unresolved difficult problem of the last century. Uncertainties of the anatomical, physiological, pathological changes and surgical techniques in the intra hepatic biliary tract contribute to this complexity. Through integrated application of modern scientific technology and traditional medicine methods and systematic optimization and innovation of biliary surgical theories and techniques, authors have developed a paradigm of precision biliary surgery which is characterized by high quantification, visualization and controllability. The establishment of the precise biliary surgical system solves the difficulty in surgeries for intrahepatic biliary diseases, puts forward the biliary surgery from extrahepatic ducts, hilar ducts to intrahepatic ducts, entering a new segment era of the biliary surgery marked by precision treatment of intrahepatic biliary diseases.