Abstract: Inflammatory bowel disease (IBD) is a bowel disease with uncontrolled inflammation and unknown etiology. With the recent expert consensus, multidisciplinary collaborative groups focusing on IBD have been gradually built in China, and IBD is not only an internal medical disease anymore. Furthermore, the therapeutic effect of IBD has also been greatly improved, but it is still not satisfactory. Precision therapy is the future direction of treatment for IBD, meanwhile, stem cell therapy and fecal transplantation also provide the new choices for refractory IBD.