胃食管反流病的外科治疗策略

Strategies on surgical treatment of gastroesophageal reflux disease

  • 摘要: 胃食管反流病(GERD)是上消化道内容物反流进入食管引起的疾病,欧美国家常见,我国发病率也逐年升高,严重影响患者生命质量。质子泵抑制剂抑酸效果明显,但GERD发病机制复杂,危险因素众多,患者需加大药物剂量或联合其他药物,治疗效果不一。因此,仍有较多GERD患者需行外科治疗,从而摆脱或减少药物治疗。外科医师在掌握手术操作规范化的同时,更应明确手术适应证,全面了解GERD发病机制,制订标准治疗流程,加强多学科团队建设,加强随访工作及数据库建立,从而更好地指导GERD的治疗。

     

    Abstract: Gastroesophageal reflux disease (GERD) is a common disease with contents of upper gastrointestinal tract reflux into esophagus. GERD is a frequently encountered problem in Western populations. Now, GERD is also common in China. Although the effect of proton pump inhibitor acid suppression was significant, there were complex pathogenesis of GERD and many risk factors, and patients need to increase the dose of the drug or in combination with other drugs. So more patients need surgical treatment to avoid or reduce the dose of drug treatment. Surgeons performing operation of the standardization should comprehensively understand the indications of surgery and pathogenesis of GERD, meanwhile, the standard treatment process, multidisciplinary team, follow up and database should be built or strengthened in order to guide the treatment of GERD.

     

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