切割闭合器在经脐单孔腹腔镜肝左外叶切除术中的应用价值

Application value of cutter stapler in transumbilical single port laparoscopic left lateral lobectomy

  • 摘要: 目的:探讨切割闭合器在经脐单孔腹腔镜肝左外叶切除术中的应用价值。
    方法:采用回顾性队列研究方法。收集2010年1月至2016年2月中国医科大学附属盛京医院收治的26例行经脐单孔腹腔镜肝左外叶切除术患者的临床资料。9例患者应用超声刀切割肝实质设为超声刀组,17例患者应用切割闭合器切割肝实质设为切割闭合器组。观察指标:(1)手术情况:手术时间、术中出血量、术后并发症发生情况、术后肠功能恢复时间、术后腹腔引流管拔除时间及术后住院时间。(2)术后复查及随访情况:术后患者必要时行超声或CT检查,观察有无局部渗出或包裹性积液形成。所有患者术后1~3个月采用电话方式进行随访,随访内容包括有无腹胀、腹痛不适等临床症状,随访时间截至2016年3月。正态分布的计量资料以±s表示,采用t检验;偏态分布的计量资料以M(范围)表示,采用秩和检验;计数资料比较采用Fisher确切概率法。
    结果:(1)手术情况:26例患者均顺利完成经脐单孔腹腔镜肝左外叶切除术,无中转多孔或开腹手术。26例患者手术时间为(114±54)min,术中出血量为100(20~800)mL,均无术中输血。超声刀组患者手术时间为(135±43)min,术中出血量为200(20~800)mL,切割闭合器组患者手术时间为(103±57)min,术中出血量为100(20~300)mL,两组患者上述指标比较,差异均无统计学意义(t=1500,Z=-0961,P>005)。两组患者术后均恢复顺利,无术后出血、胆汁漏、切口感染等并发症发生,无死亡病例。超声刀组患者术后肠功能恢复时间、术后腹腔引流管拔除时间及术后住院时间分别为(15±04)d、(58±20)d和(70±20)d,切割闭合器组为(11±03)d、(41±11)d和(49±14)d,两组患者上述指标比较,差异均有统计学意义(t=2599,2875,3036,P<005)。(2)术后复查及随访情况:26例患者中,11例患者术后行腹部超声或CT检查,均提示肝切缘周围无或仅少许液体渗出,未予特殊处置。其余15例患者未行超声或CT检查。26例患者均获得术后随访,随访时间为1~3个月。患者术后均无明显腹上区腹胀或腹痛不适等临床症状。
    结论: 经脐单孔腹腔镜肝左外叶切除术安全可行,术中切割闭合器的应用有助于手术安全、顺利地完成,促进患者术后恢复。

     

    Abstract: Objective:To investigate application value of cutter stapler in transumbilical single port laparoscopic left lateral lobectomy.
    Methods:The retrospective cohort study was adopted. The clinical data of 26 patients who underwent transumbilical single port laparoscopic left lateral lobectomy at the Shengjing Hospital of China Medical University from January 2010 to February 2016 were collected. Nine patients who received liver parenchyma using ultrasonic knife were allocated into the ultrasonic knife group, 17 patients who received liver parenchyma using cutter stapler were allocated into the cutter stapler group. Observation indicators included (1) operation situations: operation time, volume of intraoperative blood loss, postoperative complications, time of postoperative bowel function recovery, time of abdominal cavity drainage tube removal, duration of postoperative hospital stay. (2) Postoperative reexamination and followup: ultrasound or computed tomography (CT) examination was performed when necessary for detecting local exudation or encapsulated effusion. The patients were followed up at postoperative 1 to 3 months with telephone interview for whether with abdominal distension or abdominal pain till March 2016. Measurement data with normal distribution were presented as ±s and analyzed by using t test. Measurement data with skewed distribution were presented as M (range) and analyzed by ranksum text. Comparison of count data was analyzed by the Fisher′s exact probility.
    Results:(1) Operation situations: all the 26 patients received transumbilical single port laparoscopic left lateral lobectomy with no conversion to porous laparoscopic surgery or open surgery. The operation time was (114±54)minutes, the volume of intraoperative blood loss was 100 mL (range, 20-800 mL), and no intraoperative blood transfusion was adopted. The operation time and volume of intraoperative blood loss were (135±43)minutes and 200 mL (range, 20- 800 mL) in the ultrasonic knife group, (103±57)minutes and 100 mL (range, 20-300 mL) in the cutter stapler group, respectively, showing no statistically significant difference between the 2 groups (t=1500, Z= -0961, P>005). All the 26 patients recovered well after surgery, with no postoperative complications as postoperative hemorrhage, bile leakage, incision infection or death. The time of postoperative bowel function recovery, time of abdominal cavity drainage tube removal and duration of postoperative hospital stay was (15±04)days, (58±20)days and (70±20)days in the ultrasonic knife group, (11±03)days, (41± 11)days and (49±14)days in the cutter stapler group, respectively, showing statistically significant differences between the 2 groups (t=2599, 2875, 3036, P<005). (2) Postoperative reexamination and followup: of 26 patients, 11 patients received ultrasound or CT examination after surgery and detected no obvious local exudation or encapsulated effusion, with no special treatment. The other 15 patients didn′t receive ultrasound or CT examination. All the 26 patients were followed up for 1-3 months, with no occurrence of upper abdominal distension or abdominal pain.
    Conclusion:Transumbilical single port laparoscopic left lateral lobectomy is safe and feasible, the application of cutter stapler is helpful to safety and success of the operation, further accelerating the postoperative recovery of patients.

     

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