提高门静脉高压症外科手术疗效的策略

Strategies to improve the surgical treatment of portal hypertension

  • 摘要: 门静脉高压症外科治疗的目的是控制食管胃底曲张静脉破裂造成的致命性出血。手术时机和手术方式的选择依赖于肝脏储备功能,除肝功能Child-Pugh分级和终末期肝病模型(MELD)评分外,剩余肝脏体积和前白蛋白是十分重要的评估参数。手术方式的选择要依据门静脉系血流动力学的参数,才能降低术后肝性脑病和再出血的发生率。肝静脉压力梯度是预测出血风险和门静脉高压程度最为重要的客观参数。 

     

    Abstract: The surgical treatment for portal hypertension (PHT) aims to control and prevent the gastroesophageal variceal bleeding. The choices of surgical timing and procedures are dependent on the liver reserve function. Except for Child-Pugh classification and model for end-stage liver disease scoring system, the future liver remrant and pre-albumin are the important evaluation indexes, meanwhile, the choice of surgical procedures would be dependent on portal hemodynamics that can reduce incidence of rebleeding of postoperative hepatic encephalopathy. Hepatic venous pressure gradient is the most important objective index forecasting bleeding risk and severity of PHT.

     

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