Abstract: The traditional distal pancreatosplenectomy (DPS) has been the standard surgical procedure for the treatment of resectable pancreatic carcinoma of body and tail. With the development of medical technology, however, the results including the rate of R0resection, number of lymph nodes dissected and postoperative 5-year survival rate were not significantly improved after DPS. According to pancreatic anatomy and phylembryogenesis, combined with renewed tumor treatment concept,the radical antegrade modular pancreatosplenectomy (RAMPS) was put forward after continuous exploration of pancreatic surgeons to improve prognosis of patients with pancreatic carcinoma of body and tail. Compared with DPS, RAMPS has advantages of R0resection rate and regional lymphadenectomy and might become the standard surgical procedure.