Abstract: Liver transplantation (LT) is one of the most important curative treatment for hepatocellular carcinoma (HCC). In the past decade, great achievements have been made in the field of liver transplantation in China. The incidence of postoperative complications and hospital mortality have significantly decreased due to growing experience and maturity of surgical techniques. However, tumor relapse after LT still negatively impact on the long-term outcome of patients with HCC. HCC recurrence and patients′ survival after LT are closely related to preoperative screening of patients, listing priority, local treatment and postoperative management. Successful management of these procedures determines the final therapeutic effect of LT on patients with HCC. In this article, the above issues were explored and discussed according to the current situation of domestic transplant community through revision of the literatures in combination with the clinical experiences.