胃造口双管法在十二指肠破裂修复术中的临床应用

Application of doubletube gastrostomy in the repair of duodenal rupture

  • 摘要: 目的:探讨胃造口双管法在外伤性十二指肠破裂修复术中的应用价值。
    方法:采用回顾性队列研究方法。收集2005年1月至2015年1月重庆市急救医疗中心收治的41例行十二指肠破裂修补术患者的临床资料。2005年1月至2009年12月收治的25例患者十二指肠减压和空肠营养管放置方法采用Hassan三管法设为三管组,2010年1月至2015年1月收治的16例患者采用胃造口双管法设为双管组。患者采用十二指肠破裂缝合修补、带蒂空肠片以及十二指肠端端吻合的方法行十二指肠修复术。患者术后予以抗感染、抗休克、生长抑素抑制分泌、营养支持及防治并发症等常规治疗。术后48 h开始经肠内营养管泵注营养液500 mL/d,渐进性增加泵注量并逐步过渡到全肠内营养支持治疗,同时收集引流的消化液回输入营养管。观察两组患者术中情况:手术方式、手术时间、术中出血量。术后情况:并发症(十二指肠瘘、腹腔感染、切口感染、肺部感染、肠梗阻)、营养管拔除时间及住院时间。正态分布的计量资料以±s表示,组间比较采用独立样本t检验。计数资料比较采用χ2检验或Fisher确切概率法检验。
    结果:41例患者中行十二指肠破裂缝合修补术28例、带蒂空肠片修补术8例、十二指肠端端吻合术5例;患者术中均行十二指肠减压及放置空肠内营养管。三管组患者手术时间为(184±38)min,双管组为(153±37)min,两组比较,差异有统计学意义(t=2.566,P<0.05)。三管组和双管组患者术中出血量分别为(1 112±707)mL和(1 011±595)mL,两组比较,差异无统计学意义(t=0.476,P>0.05)。三管组和双管组患者术后十二指肠瘘、腹腔感染、切口感染、肺部感染发生比例分别为3/25和1/16、8/25和5/16、9/25和4/16、10/25和 6/16,两组患者上述指标比较,差异均无统计学意义(χ2=0.003,0.545,0.026,P>0.05)。术后11例患者发生早期肠梗阻,其中三管组10例(十二指肠部分狭窄3例、空肠造口附近小肠不全梗阻7例),双管组 1例(十二指肠部分狭窄);两组患者术后早期肠梗阻发生比例比较,差异有统计学意义(P<0.05)。早期肠梗阻患者均经胃肠减压、禁食等保守治疗后缓解。三管组患者肠内营养管留置时间和住院时间分别为(25±9)d和(29±9)d,双管组分别为(19±9)d和(23±8)d,两组比较,差异均有统计学意义(t=2.188, 2.120,P<0.05)。
    结论:十二指肠破裂修复术中,采用胃造口双管法放置十二指肠减压管和空肠营养管,简化了手术步骤,可缩短手术时间和术后恢复时间,降低术后肠梗阻风险,近期疗效可靠。

     

    Abstract: Objective:To investigate the application value of doubletube gastrostomy in the duodenal rupture repair.
    Methods:The retrospective cohort study was adopted. The clinical data of 41 patients who underwent duodenal rupture repair at the Chongqing Emergency Medical Center from January 2005 to January 2015 were collected. Twentyfive patients using Hassan tripletube gastrostomy technique between January 2005 and December 2009 were divided into the tripletube (TT) group and 16 patients using doubletube gastrostomy technique between January 2010 and January 2015 were divided into the doubletube (DT) group. Duodenal rupture repair included suture repair, pedicled ileal flap to repair duodenal defect and end to end anastomosis. Patients underwent the regular treatments of antiinfection, antishock, somatostatin inhibition, nutritional support and complications prevention. Patients were injected with 500 mL/d nutrient solution using enteral nutritional tube from 48 hours after operation, and then dosage was gradually increased to total enteral nutrition and digestive juices collected from drainage fluid were transfused to enteral nutritional tube. The postoperative complications (duodenal fistula, intraperitoneal infection, incision infection, pulmonary infection and intestinal obstruction), operation method, operation time, volume of blood loss, enteral nutritional tube removal time and duration of hospital stay were observed. Measurement data with normal distribution were presented as ±s and comparison between groups was analyzed using an independent sample t test. Comparison of count data was analyzed using chisquare test or Fisher exact probability.Results:All the 41 patients underwent duodenal rupture repair, including 28 using suture repair of duodenal rupture, 8 using pedicled ileal flap to repair duodenal defect and 5 using end to end anastomosis, with the intraoperative duodenal decompression and placement of intestinal feeding tube. The operation time was (184±38)minutes in the TT group and (153±37)minutes in the DT group, with a significant difference between the 2 groups (t=2.566, P<0.05). The volume of intraoperative blood loss was (1 112±707)mL in the TT group and (1 011±595)mL in the DT group, with no significant difference between the 2 groups (t=0.476, P>0.05). The proportions of duodenal fistula, intraperitoneal infection, incision infection and pulmonary infection in the TT and DT groups were 3/25 and 1/16, 8/25 and 5/16, 9/25 and 4/16, 10/25 and 6/16, respectively, showing no significant difference between the 2 groups (χ2=0.003, 0.545, 0.026, P>0.05). Eleven patients were complicated with postoperative early intestinal obstruction, including 10 (3 with partial duodenal stenosis and 7 with incomplete small intestinal obstruction) in the TT group and 1 (partial duodenal stenosis) in the DT group, showing a significant difference in the incidence of postoperative early intestinal obstruction between the 2 groups (P<0.05). Patients with early intestinal obstruction had remission after conservative treatment of gastrointestinal decompression and fasting. The time of intestinal feeding tube indwelling and duration of hospital stay were  (25±9)days and (29±9)days in the TT group, (19±9)days and (23±8)days in the DT group, with significant differences between the 2 groups (t= 2.188, 2.120, P<0.05).
    Conclusion:Doubletube gastrostomy technique for duodenal rupture repair can simplify the operation procedures and reduce operation time, recovery time and risk of postoperative intestinal obstruction, with a reliable efficacy.

     

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