Abstract: Colorectal cancer is a kind of common malignant tumor, the incidence of which appears to increase with the developments of social economy and change of life style. Liver metastasis occurred in about 50% of patients with colorectal cancer, as an important cause of death. In recent years, radiofrequency ablation (RFA) has been used clinically to damage the hepatic metastatic carcinoma. With the characteristics of accuracy, microinvasive trauma and repeatability, RFA has been extensively used as an effective local treatment. This paper discusses the indications of RFA for colorectal liver metastasis (CRLM), current status of RFA in unresectable and resectable CRLM, application of RFA in combine therapy for CRLM.