单独保留肝尾状叶解剖性肝切除治疗肝胆管结石病

Caudate lobe as the sole remnant liver following anatomical hepatectomy for the treatment of hepatolithiasis

  • 摘要: 目的:探讨单独保留肝尾状叶解剖性肝切除术治疗肝胆管结石病的安全性及近期疗效。
    方法回顾性分析2014年4月湖南省人民医院收治的1例肝胆管结石病合并肝萎缩肥大复合征患者的临床资料。结石位于患者左、右半肝,受累肝脏萎缩纤维化,不含结石的肝尾状叶肥大。术前评估患者体表面积为1.65 m2,标准肝脏体积为1 167.63 mL。根据CT检查预计肝切除术后剩余肝脏(肝尾状叶)体积为706.12 mL,剩余肝脏体积占标准肝脏体积的60.47%。剩余肝脏占体质量的1.21%。患者行再次胆道探查取石,单独保留肝尾状叶肝切除,胆总管T管引流术。术后采用门诊和电话方式进行随访,随访患者结石复发情况,随访时间截至2015年4月。
    结果:患者成功行单独保留肝尾状叶解剖性肝切除术,手术时间为380 min,术中出血量为350 mL,未输血。术后第2天拔除腹腔引流管,肝功能恢复良好,第8天出院。术后病理学检查结果:灶状胆管上皮乳头状增生伴轻中度非典型增生,未见癌变。患者术后2个月T管造影检查胆管下端通畅,肝内外无结石残留,肝功能正常,拔除T管,恢复正常生活。随访1年,患者无寒战、发热、黄疸和腹痛;B超检查未发现结石,复查CT示剩余肝脏体积增大,肝内外胆管未见结石影。
    结论 单独保留肝尾状叶解剖性肝切除术治疗肝胆管结石病安全可行,疗效优良。

     

    Abstract: Objective:To investigate the safety and shortterm effect of anatomical hepatectomy for the treatment of hepatolithiasis with the caudate lobe as the sole remnant liver.
    Methods:The clinical data of 1 patient with hepatolithiasis combined with liver atrophyhypertrophy syndrome who was admitted to the Hunan Provincial People′s Hospital in April 2014 were retrospectively analyzed. The stones were located in the left and right liver, the involved liver became fibroatrophy, and the hepatic caudate lobe not containing stones became hypertrophy. The body surface area of the patient was 1.65 m2, standard total liver volume was 1 167.63 mL. According to the result of CT, expected residual liver volume after hepatectomy was 706.12 mL, and the ratio of residual liver volume over the standard total liver was 60.47%. The radio of residual liver volume over the body mass index was 1.21%. The patient received the second exploration of common bile ducts, hepatectomy with the caudate lobe as the sole remnant liver and T tube drainage. The followup including recurrence of calculus was performed by outpatient examination and telephone interview up to April 2015.
    Results:The patient underwent caudate lobe as the sole remnant liver following anatomical hepatectomy successfully without blood transfusion. The operation time and volume of intraoperative blood loss were 380 minutes and 350 mL. The peritoneal drainage tube was removed at postoperative day 2 and the patient was discharged at postoperative day 8 with a good recovery of liver function. The postoperative pathological examination showed that there were focal biliary epithelial papillary hyperplasia combined with lightmedium atypical hyperplasia and no canceration. The T tube cholangiography two month later showed that there were unobstructed lower bile duct and no residual intra and extrahepatic stones. The liver function was normal. Then T tube was removed and patient resumed normal life. During the 1year followup, no chills and fever, jaundice and abdominal pain occurred, no calculus was detected by Bultrasonography, and computed tomography reexamination showed that remnant liver volume was increased and no intra and extrahepatic bile duct stones were detected.
    Conclusion:Anatomical hepatectomy for the treatment of hepatolithiasis with the caudate lobe as the sole remnant liver is safe and feasible, with a good curative effect.

     

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