脾动脉瘤的介入治疗

Interventional treatment for splenic artery aneurysm

  • 摘要: 目的:探讨介入治疗脾动脉瘤的临床价值和疗效。
    方法:回顾性分析2009年1月至2014年12月上海交通大学医学院附属第九人民医院收治的14例脾动脉瘤患者的临床资料。患者术前行CT血管造影检查评估脾动脉瘤的大小、性状,脾动脉载瘤动脉的直径,动脉瘤所处脾动脉的位置、形状及瘤颈大小。根据患者术前影像学检查结果,选择合适的介入栓塞方法。栓塞治疗后患者行脾动脉DSA检查显示载瘤动脉通畅,脾脏正常显影,瘤腔内无造影剂滞留显影亦无造影剂外溢,则为介入栓塞治疗成功。患者出院后1个月和半年在门诊各复查CT血管造影检查1次。随访时间截至2015年6月。
    结果:14例患者中,共发现15个动脉瘤,1例为多发,13例为单发。2个为假性动脉瘤,13个为真性动脉瘤,瘤体多呈圆形或椭圆形。动脉瘤的位置:位于脾动脉近心端5个,位于中段7个,位于远心端3个。瘤体直径为1.6~ 7.5 cm,平均为3.7 cm。14例患者均顺利运用弹簧圈栓塞治疗。1例真性脾动脉瘤患者因为动脉瘤开口较大,选用裸支架联合弹簧圈栓塞治疗成功。1例多发真性动脉瘤患者同时栓塞瘤腔开口远心端和近心端的载瘤动脉,并在瘤腔置入裸支架治疗。1例真性脾动脉瘤患者因载瘤动脉扭曲,且瘤腔开口较大,选用同轴微导管联合球囊行弹簧圈栓塞治疗成功。14例患者术后无恶心、呕吐等消化道症状,皮下注射低分子肝素至出院。术后随访情况:术后1个月,1例患者出现脾梗死;3例患者出现一过性轻微腹痛及低热;其余患者恢复良好,未见瘤腔复通及增大。术后6个月,2例患者辅助支架无移位,其余无不良反应。
    结论:脾动脉瘤介入治疗操作简单,手术安全、有效,患者恢复快、并发症少,同时保留了脾脏功能,具有良好的推广应用前景。

     

    Abstract: Objective:To explore the clinical value and efficacy of interventional treatment for splenic artery aneurysm (SAA).
    Methods:The clinical data of 14 patients with SAA who were admitted to the Shanghai Ninth People′s Hospital Affiliated to Shanghai Jiaotong University from January 2009 to December 2014 were retrospectively analyzed. The size, characteristic, diameter of splenic parent artery and location, shape and neck size of SAA in splenic artery were evaluated by preoperative computed tomography angiography (CTA). The proper interventional embolization was selected according to the results of preoperative imaging. The success of interventional embolization was confirmed by the results of digital subtraction angiography (DSA) of splenic artery including unobstructed parent artery, normal imaging of spleen and no retention and overflowing of contrast agent in the aneurismal cavity. All the patients received the outpatient reexaminations of CTA at postdischarged month 1 and month 6. The followup was performed up to June 2015.
    Results:Of the 14 patients, 15 SAAs were detected, including 1 multiple SAA and 13 single SAAs. There were 2 pseudoaneurysms and 13 true aneurysms, and most of the aneurismal bodies were roundor ovalshaped. Five SAAs were located at the proximal ends of splenic artery, 7 at the middle ends of splenic artery and 3 at the distal ends of splenic artery. The diameter of aneurysm was 1.6-7.5 cm with a median of 3.7 cm. Fourteen patients received successful embolization with detachable coils. One patient with true SAA underwent successful embolization using bare metal stent (BMS) combined with detachable coils due to the large opening of SAA. One patient with multiple true SAA received simultaneous embolization on the parent artery of the proximal and distal ends of aneurismal cavity opening and a placement of BMS in the aneurismal cavity. One patient with true SAA underwent successful embolization using coaxial microcatheter combined with detachable coils in the balloon due to parent artery twist and large opening of SAA. Fourteen patients received postoperative subcutaneous injection of low molecular weight heparin till discharge without digestive tract symptoms such as nausea and vomiting. The results of followup: 1 patient was complicated with splenic infarction, 3 with temporary abdominal pains and low fever and other patients with good recovery and without recurrence and enlargement of aneurismal cavity at postoperative month 1. No assistedstent displacement of 2 patients and no adverse reaction occurred at postoperative month 6.
    Conclusions: Interventional therapy of SAA is feasible, safe and effective, with the advantages of faster recovery of patients, less complications, preservation of the spleen function and a good application value.

     

/

返回文章
返回