克罗恩病诊断延迟的危险因素及其对预后的影响
Risk factors of diagnostic delay of Crohn′s disease and their impact on prognosis
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摘要:
近年来随着我国克罗恩病发病率的攀升，临床医师开始逐渐认识并重视该疾病。目前暂无根治克罗恩病的有效手段，且其并发症种类繁多，准确诊断后早期治疗干预疾病的进展显得尤为重要。然而受多种因素限制，诊断延迟问题在全世界范围内广泛存在。确诊年龄<40岁、女性、存在回肠病变、使用非甾体类抗炎药、吸烟史、肠外症状等因素是克罗恩病诊断延迟的危险因素。而诊断延迟可使克罗恩病患者的并发症，尤其是肠道狭窄和接受相关手术的风险明显增加。诊断延迟问题亟待全社会，特别是医务工作者的重视，患者和临床医师可采取有效措施及时诊断和早期干预，以期改善患者的预后。
Abstract:With the rise of the incidence of Crohn′s disease, clinicians began to recognize and pay attention to this disease. There is no effective method to cure the Crohn′s disease currently, and the complications of the Crohn′s disease are numerous and complex. Therefore, early diagnosis and treatment are very important. Due to many factors, the problem of diagnostic delay is widespread. Female patients diagnosed younger than 40 years old, the presence of ileal disease, use of nonsteroidal antiinflammatory agents, smoking history, parental symptoms are risk factors of diagnostic delay of Crohn′s disease. Delayed diagnosis might increase the risk of complications, especially intestinal stenosis and operationrelated complications. Crohn′s disease needs to be early diagnosed and treated to improve the prognosis of patients.
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Keywords:
- Crohn′s disease /
- Diagnostic delay /
- Risk factors /
- Complications
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