Abstract: The incidence of obesity increases worldwide every year, positioned as an important disease by WHO, and it has become an important public health problem. National survey shows that overweight and obesity rates were 22.8% and 7.1% respectively in Chinese adults in 2002, affecting 270 million people. At present, bariatric surgery is a safe and effective treatment for severe obese patients. In July 2011, a patient with Ⅲ degree obesity (weight 148 kg and BMI 51 kg/m2) complicated with type 2 diabetes mellitus was admitted to the Third Xiangya Hospital of Central South University. The treatment plan was made after diagnosis and treatment of multidisciplinary team and the patient underwent laparoscopic sleeve gastrectomy. The patient was followed up to September 2012 and recovered well without severe surgical complications, and the weight and BMI were decreased to 75 kg and 25 kg/m2 respectively.