慢性便秘患者多学科团队评估的临床意义

Clinical value of multidisciplinary team assessment for chronic constipation

  • 摘要: 目的:探讨对慢性便秘患者进行多学科团队(MDT)评估的临床意义。
    方法:选取2010年1月至2013年12月杭州市第三人民医院收治的346例慢性便秘患者进行前瞻性研究,采用临床调查研究法对入组患者进行肛肠外科、泌尿外科、妇科、精神心理科的多学科临床特征评估,包括问卷调查、排粪造影、肛门测压、结肠运输功能试验、尿流动力学、妇科等检查。正态分布的计量资料采用±s表示,组间的比较采用方差分析,计数资料比较采用χ2检验。
    结果:筛选出符合本研究条件的患者346例,男86例,女260例,男女比例为1〖DK〗∶3;年龄为(55±11)岁。346例患者中慢传输型便秘占7.52%(26/346)、排便障碍型便秘占60.98%(211/346)、混合型便秘占31.50%(109/346)。93.85%(244/260)的女性患者存在直肠前突,75.43%(261/346)的患者存在直肠黏膜内脱垂,66.76%(231/346)的患者存在会阴下降,23.99% (83/346)的患者存在内括约肌失迟缓或排便时反常收缩,18.79%(65/346)的患者存在耻骨直肠肌肥厚,5.49%(19/346)的患者存在直肠外脱垂。82.37%(285/346)的患者存在肛肠外科之外的疾病。28.61%(99/346)的患者伴有泌尿系统症状,其中压力性尿失禁65例、不稳定性膀胱23例、膀胱出口梗阻19例(部分患者合并多项泌尿系统症状)。女性患者中生殖器官脱垂发生率为31.92%(83/260),其中子宫脱垂发生率为26.15%(68/260),阴道前壁膨出发生率为29.23%(76/260)。心理评估后发现焦虑和(或)抑郁患者占36.13%(125/346)。慢传输型便秘、排便障碍型便秘、混合型便秘患者男女各10例和16例、 30例和79例、46例和165例,3种类型便秘患者年龄分别为(60±12)岁、(56±11)岁、(52±10)岁,3者男女性别比例、年龄比较,差异无统计学意义(χ2=4.046,F=2.877,P>0.05)。3种类型便秘患者中,合并泌尿外科疾病患者比例分别为 26.92%(7/26)、26.61%(29/109)和29.86%(63/211),合并妇科疾病患者比例分别为11.54%(3/26)、20.18%(22/109)、27.49%(58/211),合并心理疾病患者比例为38.46%(10/26)、39.45%(43/109)、34.12%(72/211),3类患者在合并泌尿外科、妇科、心理疾病3方面比较,差异无统计学意义(χ2=4.090,P>0.05)。
    结论:对慢性便秘患者的MDT评估能够较全面地反映慢性便秘的临床特点;该病临床诊断应该注重MDT的合作。

     

    Abstract: Objective:To investigate the clinical value of multidisciplinary team (MDT) assessment for chronic constipation.
    Methods:The clinical characteristics of 346 patients with chronic constipation who were admitted to the Third Peolep′s Hospital of Hangzhou from January 2010 to December 2013 were multidisciplinarily assessed. The multidisciplinary team was involved surgeons from the department of colorectal surgery, urology, gynecology, psychiatry and psychology, and tools including questionnaires, defecography, anorectal manometry, colon transit study, urodynamic tests, gynecological examination were applied in the study. The measurement data with normal distribution were presented as ±s, the comparison between groups was analyzed using the ANOVA, and the count data were analyzed using the chisquare test.
    Results:Three hundred and fortysix patients who met criteria of this research were selected, including 86 males and 260 females with the ratio of 1〖DK〗∶3; the mean age was (55±11)years. Of the 346 patients, slow transit constipation accounted for 7.52%(26/346), defecatory disorder for 60.98%(211/346), and mixed constipation for 31.50%(109/346). A total of 93.85% female patients (244/260) had anterior rectocele, 75.43%(261/346) patients had internal rectal mucosal prolapse, 66.76%(231/346) patients had perineum descending, 23.99%(83/346) had achalasia or inappropriate contraction of internal anal sphincter, 18.79%(65/346) had puborectalis rectocele muscle thickening, 5.49%(19/346) had rectal prolapse. A total of 82.37%(285/346) patients were involved in other subjects than colorectal surgery. A total of 28.61%(99/346) patients presented with urinary symptoms, including 65 cases with stress urinary incontinence, 23 cases with unstable bladder and 19 cases with bladder neck obstruction (some patients had multiple urological systoms). The incidence of reproductive organ prolapse in female patients was 31.92% (83/260), the incidence of uterine prolapse and anterior vaginal prolapse were 26.15%(68/260) and 29.23%(76/260), respectively. Patients with anxiety and/or depression accounted for 36.13%(125/346). The male and female patients of slow transit constipation, defecatory constipation and mixed constipation were 10 vs 16, 30 vs 79, 46 vs 165, respectively, the age was 60±12, 56±11, 52±10, showing no significant differences (χ2=4.046, F=2.877, P>0.05). In the three kinds of constipation, patients with urinary diseases accounted for 26.92%(7/26), 26.61%(29/109) and 29.86%(63/211), patients with gynecological diseases accounted for 11.54%(3/26), 20.18%(22/109), 27.49%(58/211), patients with psychological diseases accounted for 38.46%(10/26), 39.45%(43/109), 34.12%(72/211), respectively, showing no significant difference (χ2=4.090, P>0.05).
    Conclusion:MDT assessment for patients with chronic constipation can reflect comprehensively clinical characteristics of chronic constipation, therefore multidisciplinary team should be emphasized in clinical diagnosis and treatment of chronic constipation.

     

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