Abstract: Hepatic cavernous hemangioma is the most common benign tumor of liver. Hepatic artery embolism chemotherapy is one of the commonly used treatment methods, but more and more related complications and sequelae have been reported recently, including obstructive jaundice caused by damaged biliary tract. Because the symptoms are not typical, obstructive jaundice might be misdiagnosed as malignant biliary tumor, which brought troubles to subsequent treatment. In this article, the clinical data of 2 patients with obstructive jaundice following transcatheter hepatic arterial chemoembolization for hepatic cavernous hemangioma were retrospectively analyzed, and the experience in the diagnosis and treatment of this disease was summarized.