Abstract: Adenomyomatosis of the gallbladder (GAM) is an acquired, benign proliferative lesion of the gallbladder which is characterized by mucosal proliferation with invaginations and diverticula penetrating into the thickened muscular layer (RokitanskyAschoff sinuses). GAM consists of 3 types: diffuse, segmental and fundus GAM. There is no specific presentation of GAM, and computed tomography is helpful for the diagnosis of this disease. From July 2010 to May 2013, 16 patients with fundus GAM were admitted to the Second People′s Hospital of Wuxi. RokitanskyAschoff sinuses and calotte sign at the thickened muscular layer of the fundus of the gallbladder are the typical presentation of the fundus GAM. Enhanced computed tomography examination is of great importance for the diagnosis of the fundus GAM.