Abstract: Hepatic eosinophilic granuloma (HEG) is a rare benign liver disease, which belongs to histocytosis. Preopera tive diagnosis of HEG was difficult because its clinical manifestation was not characteristic. In this article, the clinical data of 1 patient with HEG who was treated at the Jinhua Municipal Central Hospital of Zhejiang Province in September 2012 were retrospectively analyzed, and the diagnosis, differential diagnosis and treatment for HEG were investigated.