Abstract: Hepatobiliary cystadenoma is a rare tumor which has malignant potential. The clinical symptoms of hepatobiliary cystadenoma were non specific. The features of computed tomography (CT) and magnetic resonance imaging (MRI) were helpful for the diagnosis of this disease. The imaging data of 4 patients with hepatobiliary cystadenoma who were admitted to the second People′s Hospital of Wuxi from February 2010 to February 2013 were retrospectively analyzed. Cystic lesions, divisions and nodules on the wall are the features of CT and MRI of hepato biliary cystadenoma. Enhanced CT and MRI are important for preoperative diagnosis of hepatobiliary cystadenoma.