Abstract: Liver metastasis is one of the critical prognostic factors for colorectal cancer. Complete surgical resection of liver metastases still remains the only potentially curative treatment for patients with liver metastases. There are still some controversies in how to choose the reasonable management for resectable colorectal cancer patients with simultaneous liver metastases, although neoadjuvant chemotherapy, tumor physical ablation technique and minimally invasive technology have made progress in recent years. One case of surgical treatment of synchronous rectal cancer liver metastasis at the Shengjing Hospital with laparoscopic microwave ablation+radical resection of colo rectal cancer was disused in order to provide reference for individualized treatment for patients with the same disease.