Advanced colorectal cancer mainly classified as locally advanced, locally recurrent and distally metastatic colorectal cancer. Distal metastasis of colorectal cancer includes peritoneal metastasis, liver, lung and other organ metastasis. Surgical resection remains the only possible cure for patients with advanced colorectal cancer. Preoperative systemic evaluation based on radiographic images, especially the evaluation on the resectability of hepatic metastatic lesions from colorectal cancer is very important. Neo-adjuvant and adjuvant therapy increased the resection rate of primary and metastatic lesions of advanced colorectal cancer. In recent 10 years, with the development of oncological surgery, treatment modality of multi-disciplinary team has been proposed and implemented, which increased the  survival time and improved the life quality of patients with colorectal cancer.