Colorectal cancer is one of the most common malignancies in human. Early diagnosis is the key points in improving the prognosis of patients with colorectal cancer. The implementation of standardized operation and comprehensive treatment for advanced and late stage cancer can improve the outcome. Based on the pattern of lymph node metastasis and the concept of complete mesocolic excision, the operation of colonic cancer has entered the era of normalization and standardization. The surgical procedure of rectal cancer (especially low rectal cancer) should be individualized based on the gold standard of total mesorectal excision (TME). For hepatic metastasis of colorectal cancer, hepatectomy is currently the standard and the only potentially curative treatment method. Therefore, how to evaluate the resectability of hepatic metastasis of colorectal cancer is particularly important. Surgeons are the most important participants in the diagnosis and treatment of colorectal cancer, and standardized diagnosis and treatment is the key to improve the prognosis of patients.