Abstract:
Objective To analyze postoperative complications of duct-to-mucosa pancreaticojejunostomy and side-to-end or end-to-end pancreaticojejunostomy following pancreaticoduodenectomy.
Methods The clinical data of 342 patients who underwent pancreaticoduodenectomy at the West China Hospital of Sichuan University from June 2004 to May 2008 were retrospectively analyzed. All patients were divided into the duct-to-mucosa group (179 cases) and side-to-end or end-to-end group (163 cases) according to the styles of pancreaticojejunostomy. The relationship between the incidence and severity of postoperative complications of the 2 anastomotic styles were analyzed according to the Clavien grading system. The measurement data and the count data were analyzed using the t test or chi-square test.
Results he overall complication rate was 48.8%(167/342), and the complication rate was 38.0%(68/179) in the side-to-end group and 60.7%(99/163) in the side-to-end or end-to-end group, with a significant difference between the 2 groups (χ2=17.667, P<0.05). The incidences of grade II and grade V complications were 16.8%(30/179) and 1.1%(2/179) in the duct-to-mucosa group, which were significantly lower than 28.2%(46/163) and 5.5%(9/163) of the side-to-end or end-to-end group (χ2=6.484, 5.316, P<0.05).
Conclusion Compared with side-to-end or end-to-end pancreaticojejunostomy, duct-to-mucosa pancreaticojejunostomy is a better style with a lower incidence of postoperative complication.
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