Abstract:
Autoimmune pancreatitis (AIP) is a pancreatic manifestation of a systemic fibroinflammatory process and it is a immunoglobulin G4related sclerosing disease. The clinical features of AIP in some aspects are similar, but in other aspects are different from those clinical features of pancreatic cancer. It should be emphasized that clinical features alone cannot be used to differentiate AIP from pancreatic cancer with certainty. The 5 cardinal criteria for the diagnosis of AIP are histology, medical imaging, serology, other organ involvement and clinical response to steroid therapy. There are now 2 diagnostic criteria of AIP: the Mayo Clinic HISORt Criteria and the Asian Diagnostic Criteria by the Japanese Pancreas Society and Asan Medical Center of Korea. Corticosteroid therapy is the mainstay of therapy for AIP. Usually the patient′s response to steroid treatment is dramatic. It is still controversial whether maintenance steroid therapy should be given to a patient who has responded well to steroid treatment.
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