Abstract: Hepatic eosinophilic granuloma is a rare benign liver lesion, which results from granuloma formation due to chronic inflammation. Two patients were admitted to the Yantaishan Hospital and Yuhuangding Hospital from July 2008 to April 2012, respectively. The results of laboratory examination showed the elevation of peripheral blood eosinophils, and ultrasound examinations revealed lowecho masses in the liver and no blood flow was detected. The results of computed tomography showed hypoattenuation lesions with welldemarcated boundary. After intravenous administration of contrast angent, the lesions demostrated delayed heterogeneous enhancement with internal grid. The results of magnetic resonance imaging of 1 patient showed the lesion had slight hyperintensity to the surrounding liver parenchyma on T1weighted images, and slight high signal with low signal separation strip inside on fatsuppressed T2weighted images. An obvious high signal was detected in diffusion weighted imaging. Familiarity with the imaging characteristics and combination of the elevation of peripheral eosinophil can help surgeons to make a suggestive diagnosis.