Objective To investigate the safety and clinical efficacy of domestic single-port robotic radical resection for colorectal cancer under the ambulatory surgery model.

Methods The retrospective and descriptive study was conducted. The clinicopathological data of 12 patients who underwent domestic single-port robotic radical resection for colorectal cancer under the ambulatory surgery model at The First Affiliated Hospital of Wenzhou Medical University from March 2025 to January 2026 were collected. There were 7 males and 5 females, aged (53±9) years. Observation indicators: (1) surgical situations; (2) postoperative situations; (3) follow-up. Measurement data with normal distribution were expressed as Mean±SD, and measurement data with skewed distribution were expressed as M (range). Count data were expressed as absolute numbers.

Results (1) Surgical situations: all 12 patients successfully underwent transumbilical single-port robotic surgery, with a 12 mm trocar placed at the McBurney's point in the right iliac region as an auxiliary port and post-operative drainage port. No conversion to open surgery was required. The docking time was (39±11) minutes. For the 8 patients with left-sided colon cancer, the operation time was 204(range, 139-310) minutes, the intraperitoneal dissection time was 130(range, 78-238) minutes, and the volume of intraoperative blood loss was 5.5(range, 2.0-23.0) mL. For the 4 patients with right-sided colon cancer, the operation time was 270(range, 246-304) minutes, the intraperitoneal dissection time was 199(range, 183-336) minutes, and the volume of intraoperative blood loss was 12.5(range, 3.0-20.0) mL.(2) Postoperative situations: a full liquid diet was initiated immediately after surgery in the 12 patients. The time to postoperative first flatus was (2.6±0.5) days, the time to postoperative first defecation was (4.5±1.0) days, and the time to drainage tube removal in the right iliac region was (3.7±1.2) days. On the postoperative first day, the white blood cell count was (10.6±2.5)×10⁹/L, the neutrophil percentage was 0.83±0.07, and the hemoglobin level was (125±14) g/L. Two of the 12 pati-ents experienced mild abdominal pain and distension, which were resolved after symptomatic treatment. No serious complications such as intra-abdominal bleeding, mechanical intestinal obstruction, or anastomotic leakage occurred, and there was no perioperative death. All patients met the discharge criteria within 24 hours postoperatively and were discharged according to the ambulatory pathway. The number of lymph nodes dissected of the 12 patients was 15±4, with pericolic lymph node metastasis observed in 3 cases. Postoperative pathological TNM staging was stage Ⅰ in 6 cases, stage Ⅱ in 3 cases, and stage Ⅲ in 3 cases. There were 1, 6, and 5 cases of poorly differentiated, moderately differentiated, and well differentiated adenocarcinoma, respectively. (3) Follow-up: all the 12 patients received follow-up. During the 30-day follow-up period, none of the 12 patients developed infection-related complications such as fever, incisional erythema with purulent discharge, or aggravated abdominal pain. No readmission was required.

Conclusion Domestic single-port robotic radical resection for colorectal cancer under the ambulatory surgery model is feasible after preliminary exploration.