达芬奇机器人手术系统袖状胃切除术治疗肥胖症的临床疗效

Clinical efficacy of Da Vinci robotic sleeve gastrectomy in the treatment of obesity

  • 摘要:
    目的 探讨达芬奇机器人手术系统袖状胃切除术治疗肥胖症的临床疗效。
    方法 采用回顾性描述性研究方法。收集2021年4月至2025年3月新疆维吾尔自治区人民医院收治的253例行达芬奇机器人手术系统袖状胃切除术肥胖症患者的临床资料;男81例,女172例;年龄为34(15~63)岁;体质量指数(BMI)为40.08(26.79~66.61)kg/m2。观察指标:(1)手术及术后情况。(2)患者BMI与围手术期指标的相关性分析。(3)手术时间的影响因素分析。正态分布的计量资料以x±s表示;偏态分布的计量资料以M(范围)表示。计数资料以绝对数表示。相关性分析采用Spearman秩相关性分析。单因素和多因素分析采用线性回归模型。
    结果 (1)手术及术后情况:253例患者均行达芬奇机器人手术系统袖状胃切除术,无中转腹腔镜或开腹手术。253例患者中,联合食管裂孔疝修补术95例,联合胃底折叠术40例,联合His角重建术36例,联合胆囊切除术28例,联合腹壁疝或切口疝修补术8例,联合膈疝修补术1例;同一例患者同时行多种联合手术。253例患者手术时间为121(83~390)min,术中出血量为20(5~200)mL,术后住院时间为4(1~16)d,住院总费用为(6.5±0.8)万元,无术后30 d内再入院。5例患者发生术中及术后并发症:术中发生脾包膜撕裂1例,经止血纱布压迫后成功止血,未影响手术进程;术后发生出血2例、切口感染1例、肺部感染1例,均给予保守治疗后痊愈出院;无胃瘘等严重并发症,无二次手术。(2)患者BMI与围手术期指标的相关性分析:Spearman秩相关性分析结果示患者术前BMI与手术时间、术中出血量均呈正相关(r=0.19,0.18,P<0.05);手术时间与术中出血量呈正相关(r=0.22,P<0.05)。(3)手术时间的影响因素分析:多因素分析结果示BMI、联合手术均是影响患者手术时间的独立因素(t=2.61,5.48,95%可信区间为0.24~1.71,17.70~37.56,P<0.05)。
    结论 达芬奇机器人手术系统袖状胃切除术可应用于治疗肥胖症,围手术期并发症发生比例较低,BMI、联合手术均是影响患者手术时间的独立因素。

     

    Abstract:
    Objective To investigate the clinical efficacy of Da Vinci robotic sleeve gastrec-tomy in the treatment of obesity.
    Methods The retrospective and descriptive study was conducted. The clinical data of 253 patients with obesity who underwent Da Vinci robotic sleeve gastrectomy at People′s Hospital of Xinjiang Uygur Autonomous Region between April 2021 and March 2025 were collected. There were 81 males and 172 females, aged 34 (range, 15-63) years. The body mass index (BMI) of patients was 40.08 (range, 26.79-66.61) kg/m2. Observation indicators: (1) surgical and postoperative situations; (2) correlation analysis between BMI and perioperative indicators; (3) analysis of influencing factors for operation time. Measurement data with normal distribution were represented as Mean±SD. Measurement data with skewed distribution were represented as M(range). Count data were represented as absolute numbers. Spearman rank correlation analysis was used for correlation assessment. Univariate and multivariate analyses were performed using the linear regression model.
    Results (1) Surgical and postoperative situations: all 253 patients successfully underwent Da Vinci robotic sleeve gastrectomy without conversion to laparoscopic or open surgery. Of 253 patients, 95 cases underwent concomitant hiatal hernia repair, 40 cases underwent conco-mitant gastric fundoplication, 36 cases underwent concomitant His angle reconstruction, 28 cases underwent concomitant cholecystectomy, 8 cases underwent concomitant abdominal wall or inci-sional hernia repair, and 1 case underwent concomitant diaphragmatic hernia repair. Some patients underwent multiple concomitant procedures simultaneously. The operation time was 121 (range, 83-390) minutes, volume of intraoperative blood loss was 20 (range, 5-200) mL, duration of post-operative hospital stay was 4 (range, 1-16) days, and total hospitalization cost was (6.5±0.8)×10⁴ yuan. There was no readmission within postoperative 30 days. Five patients had intraoperative and posto-perative complications. Of them, one case with intraoperative splenic capsule tear was successfully controlled after hemostatic gauze compression without affecting the procedure. Two cases of bleeding, 1 case of wound infection, and 1 case of pulmonary infection were cured after conservative treatment and discharged from hospital. No severe complication such as gastric leakage occurred, and no reoperation was required. (2) Correlation analysis between BMI and perioperative indicators. Spearman rank correlation analysis showed that preoperative BMI was positively correlated with operation time and volume of intraoperative blood loss (r=0.19, 0.18, P<0.05). Operation time was also positively correlated with volume of intraoperative blood loss (r=0.22, P<0.05). (3) Analysis of influencing factors for operation time. Results of multivariate analysis showed that BMI and conco-mitant procedure were independent influencing factors for operation time (t=2.61, 5.48, 95% confidence interval as 0.24-1.71, 17.70-37.56, P<0.05).
    Conclusions Da Vinci robotic sleeve gastrectomy can be safely applied in the treatment of obesity, with a low incidence of perioperative complications. BMI and concomitant procedure are independent influencing factors for operation time of patients.

     

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