Abstract: Graft‑versus‑host disease (GVHD) after liver transplantation is a rare but fatal complication, with the incidence rate <1% and mortality of 85%. The occurrence of GVHD is due to the cellular immune response of donor T lymphocytes to recipient tissues, which can affect the skin, gastrointestinal tract, and bone marrow. The typical clinical manifestations of GVHD include rash, fever, diarrhea, and decreased whole blood cells. The Branch of Organ Transplant of China Medical Association, combined with Branch of Organ Transplant Physicians of Chinese Medical Doctor Associa-tion organize experts to develop the Chinese Expert Consensus On The Diagnosis And Treatment Of Acute Graft‑Versus‑Host Disease After Liver Transplantation (2024 edition), which elaborates on the pathogenesis, risk factors, clinical manifestations, diagnosis and treatment of GVHD. The aim is to standardize and optimize the clinical diagnosis and treatment of GVHD after liver transplantation, and to propose diagnostic processes and treatment suggestions to improve the prognosis of GVHD recipients after liver transplantation.