Abstract: After more than 20 years of development, pediatric liver transplantation has become a routine surgical practice in China, and currently ranks first in the world in terms of surgery quantity yearly. Further improving of liver transplantation technique and enhancing postoperative management to enable pediatric liver transplantation patients to return to normal social life are challenges for the academic community. The development of precision surgery, minimally invasive technology, big data information interconnection, and artificial intelli-gence has also brought new opportunities to researchers. The authors discuss the indications, surgical techniques, postoperative management system, immune suppression and tolerance, social humanities and ethics of pediatric liver transplantation in China, in order to promote the development of related fields of pediatric liver transplantation in China.